Enhancement of chitin suspension hydrolysis by a combination of ultrasound and chitinase

Carbohydr Polym. 2020 Mar 1:231:115669. doi: 10.1016/j.carbpol.2019.115669. Epub 2019 Nov 25.

Abstract

This study evaluated the degradation kinetics and structural characteristics of chitin suspension (CS) with a combination of ultrasound and chitinase. Compared with the enzymolysis, the degradation degree of sonoenzymolysis was enhanced to the maximum by 27.93 % at an intensity of 25 W/mL for 20 min. According to degradation kinetics, ultrasound intensified molecular collision rate between chitinase and substrate, thereby increasing the degradation degree. What's more, combined with chitinase, ultrasound intensified the rate of the breakage of glycosidic bond and viscosity-average molecular weight (Mv) decrease, but no obvious change in acetylation degree (DA). Additionally, the intra- or inter-hydrogen bindings were weakened by ultrasound during sonoenzymolysis, leading to a slight decrease in crystalline index and a more ordered structure, which increased the accessibility of the substrate to enzyme. In conclusion, combination of chitinase and ultrasound could enhance the hydrolysis of CS while without changing its primary structure.

Keywords: Chitin suspension; Degradation; Enzymolysis; Sonoenzymolysis; Structure characteristics.

MeSH terms

  • Acetylation / drug effects
  • Acetylation / radiation effects
  • Chitin / chemistry*
  • Chitin / radiation effects
  • Chitinases / chemistry*
  • Chitinases / pharmacology
  • Hydrogen / chemistry
  • Hydrolysis / radiation effects
  • Kinetics
  • Suspensions / chemistry
  • Suspensions / pharmacology
  • Ultrasonic Waves*

Substances

  • Suspensions
  • Chitin
  • Hydrogen
  • Chitinases