Statin might promote epicardial adipose tissue inflammatory remodeling via NLRP3 suppression: An intriguing hypothesis

Int J Cardiol. 2020 Feb 1:300:219. doi: 10.1016/j.ijcard.2019.10.056.
No abstract available

Keywords: Epicardial adipose tissue; Inflammation; NLRP3; Statin therapy.

Publication types

  • Letter

MeSH terms

  • Adipose Tissue / drug effects*
  • Adipose Tissue / metabolism
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology*
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • NLR Family, Pyrin Domain-Containing 3 Protein / antagonists & inhibitors*
  • NLR Family, Pyrin Domain-Containing 3 Protein / metabolism
  • Pericardium / drug effects*
  • Pericardium / metabolism

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • NLRP3 protein, human