Micronodular thymoma with lymphoid stroma: report of two cases and review of literature

Micronodular thymoma with lymphoid stroma (MNT) is a rare subtype of organoid thymic epithelial tumor that occurs in middle-aged and elderly people. Histologically, MNT is characterized by multiple epithelial nodules that are scattered or fused and abundant lymphocyte stroma with prominent germinal centers. It has a benign course and a good prognosis, and its diagnosis mainly depends on histopathologic and immunohistochemical markers. This article reports two cases of MNT to explore its clinicopathologic features, diagnosis and differential diagnosis to improve understanding of this subtype. In addition, we review previously reported cases of MNT.