Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018

Vector Borne Zoonotic Dis. 2020 Apr;20(4):314-317. doi: 10.1089/vbz.2019.2531. Epub 2020 Jan 14.

Abstract

Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity.

Keywords: Cameroon; dengue; fever; flavivirus; mosquito; virus.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Cameroon / epidemiology
  • Dengue / blood
  • Dengue / epidemiology*
  • Dengue / transmission*
  • Dengue Virus / genetics
  • Dengue Virus / isolation & purification*
  • Female
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Prevalence
  • RNA, Viral / isolation & purification
  • Risk Factors
  • Young Adult

Substances

  • RNA, Viral