Baby's First Bacteria: Discriminating Colonizing Commensals from Pathogens

Yue Xing; Shruti Naik

doi:10.1016/j.chom.2019.11.008

Baby's First Bacteria: Discriminating Colonizing Commensals from Pathogens

Cell Host Microbe. 2019 Dec 11;26(6):705-707. doi: 10.1016/j.chom.2019.11.008.

Authors

Yue Xing¹, Shruti Naik²

Affiliations

¹ Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA; Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.
² Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA; Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA. Electronic address: [email protected].

PMID: 31951581
DOI: 10.1016/j.chom.2019.11.008

Abstract

At birth, microbes rapidly colonize our epithelial surfaces. In this issue of Cell Host & Microbe, Leech et al. (2019) uncover how the neonatal immune system discriminates between a colonizing commensal and pathogen to selectively generate tolerance to commensal species.

Publication types

Comment

MeSH terms

Bacteria*
Immune Tolerance
Receptors, Interleukin-1*
Signal Transduction
Symbiosis

Substances

Receptors, Interleukin-1