Hepatitis E virus (HEV) RNA was detected in 6.3% and HEV IgG in 40% of 5,033 serum samples from market-weight pigs at 25 slaughterhouses in 10 US states. The prevalent HEV genotype was zoonotic genotype 3, group 2. Blood of HEV-viremic pigs from slaughterhouses may contaminate pork supply chains.
Keywords: HEV; HEV IgG; Hepatitis E virus; United States; genotype; market-weight pigs; pork safety; slaughterhouse; subgenotype; zoonoses.