Multicenter screening of diabetic patients for detecting new cases of tuberculosis: an approach to intensify the case detection rate of tuberculosis in developing countries with high prevalence of diabetes

J Prev Med Hyg. 2019 Dec 20;60(4):E343-E348. doi: 10.15167/2421-4248/jpmh2019.60.4.883. eCollection 2019 Dec.

Abstract

Introduction: Tuberculosis (TB) is a major public health problem in most of developing countries. Meanwhile, the prevalence of type 2 diabetes mellitus (DM) is also increasing rapidly.

Objectives: To describe the feasibility of implementing screening test for tuberculosis among diabetic patients and identifying factors associated with high detection rate.

Methods: Study Design: Multi-center cross-sectional study. This study was implemented in the governmental healthcare settings. To diagnose TB among diabetics, we used a symptom-based questionnaire that included the symptoms of suspected TB according to the guidelines of National Tuberculosis Program in Egypt.

Results: Among 4283 adult diabetics, 14 TB cases were diagnosed; 9 known TB cases and 5 newly detected cases. The number needed to detect one new case of TB was 855. Male diabetics and who those suffered from liver disease experienced a significantly higher prevalence of TB and a higher detection rate of new active cases.

Conclusions: Screening for TB among diabetics in routine governmental healthcare services was successfully implemented. Screening DM patients in countries with a high prevalence of DM will reveal a significant number of active TB cases, which will in turn improve the case detection rate of TB.

Keywords: Case detection rate; Diabetes; Screening; Tuberculosis.

MeSH terms

  • Comorbidity
  • Developing Countries*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Egypt / epidemiology
  • Feasibility Studies
  • Female
  • Humans
  • Hypertension / epidemiology
  • Liver Diseases / epidemiology
  • Male
  • Mass Screening
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Surveys and Questionnaires
  • Tuberculosis / diagnosis
  • Tuberculosis / epidemiology*