The use of statins in the elderly is associated with less severe hypoglycemia in patient with diabetes

Diabetes Res Clin Pract. 2020 Apr:162:108034. doi: 10.1016/j.diabres.2020.108034. Epub 2020 Jan 29.

Abstract

Three hundred and eighty-nine older patients with diabetes attending an ambulatory diabetes center were included to determine risk factors of severe hypoglycemia (SH). Thirty-three (8.5%) patients had at least one severe hypoglycemia. In multivariate analyze, statin was associated with lower risk and insulin was associated with higher risk of SH.

Keywords: Ambulatory care center; Elderly; Insulin; Severe hypoglycemia; Statin.

MeSH terms

  • Aged
  • Diabetes Mellitus / drug therapy*
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Hypoglycemia / drug therapy*
  • Longitudinal Studies
  • Male

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors