Health-related quality of life among tonsillar carcinoma patients in Sweden in relation to treatment and comparison with quality of life among the population

Head Neck. 2020 May;42(5):860-872. doi: 10.1002/hed.26064. Epub 2020 Feb 10.

Abstract

Background: The health-related quality of life (HRQOL) of tonsillar carcinoma survivors was explored to investigate any HRQOL differences associated with tumor stage and treatment. The survivors' HRQOL was also compared to reference scores from the population.

Methods: In this exploratory cross-sectional study patients were invited 15 months after their diagnosis and asked to answer two quality of life questionnaires (EORTC QLQ- C30, EORTC QLQ- HN35), 405 participated.

Results: HRQOL was associated with gender, with males scoring better than females on a few scales. Patients' HRQOL was more associated with treatment than tumor stage. Patients' HRQOL was worse than that in an age- and sex-matched reference group from the normal population, the largest differences were found for problems with dry mouth followed by problems with sticky saliva, senses, swallowing and appetite loss.

Conclusions: The tonsillar carcinoma patients had a worse HRQOL compared to the general population one year after treatment.

MeSH terms

  • Carcinoma*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Quality of Life*
  • Surveys and Questionnaires
  • Sweden / epidemiology