Progressive multifocal leukoencephalopathy in a patient with primary amyloid light-chain amyloidosis

Kazuto Katsuse; Kaho Akiyama; Tadao Ishida; Chigusa Kitayama; Yoshitaka Ishibashi; Mieko Ochi; Toshio Kumasaka; Kenta Takahashi; Tadaki Suzuki; Kazuo Nakamichi; Masayuki Saijo; Hideji Hashida

doi:10.1016/j.clineuro.2020.105709

Progressive multifocal leukoencephalopathy in a patient with primary amyloid light-chain amyloidosis

Clin Neurol Neurosurg. 2020 May:192:105709. doi: 10.1016/j.clineuro.2020.105709. Epub 2020 Feb 3.

Authors

Affiliations

¹ Department of Neurology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan. Electronic address: [email protected].
² Department of Neurology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan.
³ Department of Hematology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan.
⁴ Department of Nephrology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan.
⁵ Department of Pathology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan.
⁶ Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan.
⁷ Department of Virology 1, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan.

PMID: 32058201
DOI: 10.1016/j.clineuro.2020.105709

No abstract available

Keywords: Amyloid light-chain (AL) amyloidosis; End-stage renal disease; Immunosuppression; JC virus (JCV); Progressive multifocal leukoencephalopathy (PML).

Publication types

Case Reports

MeSH terms

Aged
Aphasia / physiopathology
Brain / diagnostic imaging*
Brain / pathology
Heart Failure / etiology
Heart Failure / physiopathology
Humans
Immunocompromised Host
Immunoglobulin Light-chain Amyloidosis / complications
Immunoglobulin Light-chain Amyloidosis / immunology
Immunoglobulin Light-chain Amyloidosis / therapy*
Leukoencephalopathy, Progressive Multifocal / complications
Leukoencephalopathy, Progressive Multifocal / diagnostic imaging*
Leukoencephalopathy, Progressive Multifocal / immunology
Leukoencephalopathy, Progressive Multifocal / physiopathology
Magnetic Resonance Imaging
Male
Paresis / physiopathology
Perceptual Disorders / physiopathology
Peripheral Blood Stem Cell Transplantation*
Renal Insufficiency, Chronic / etiology
Renal Insufficiency, Chronic / physiopathology