Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity

Phytochemistry. 2020 Apr:172:112276. doi: 10.1016/j.phytochem.2020.112276. Epub 2020 Feb 12.

Abstract

Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemical composition of specialized metabolites of B. monnieri and in the formulations by different analytical techniques. This comprehensive review covers literature up to 2019 with an emphasis on structural characterization of dammarane triterpenoid glycosides by spectroscopic techniques, chemical composition by analytical methods and pharmacological activities.

Keywords: Bacopa monnieri; Biological activity; Dammarane triterpenoids; Plantaginaceae; Structure elucidation.

Publication types

  • Review

MeSH terms

  • Bacopa*
  • Dammaranes
  • Glycosides
  • India
  • Plant Extracts
  • Triterpenes*

Substances

  • Glycosides
  • Plant Extracts
  • Triterpenes