Abstract
Genetic mutations linked to bedaquiline resistance were found before starting treatment and acquired during treatment in patients with drug-resistant TB and HIV in KwaZulu-Natal, South Africa. Routine bedaquiline resistance testing needs to be accelerated. http://bit.ly/2vnL4VY
Publication types
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Letter
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Antitubercular Agents / therapeutic use
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Coinfection* / drug therapy
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Diarylquinolines / therapeutic use
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HIV Infections* / complications
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HIV Infections* / drug therapy
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Humans
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Mycobacterium tuberculosis*
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Tuberculosis, Multidrug-Resistant* / complications
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Tuberculosis, Multidrug-Resistant* / drug therapy
Substances
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Antitubercular Agents
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Diarylquinolines
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bedaquiline