Choroidal neovascular membrane associated with primary congenital glaucoma and buphthalmos

J AAPOS. 2020 Feb;24(1):53-56. doi: 10.1016/j.jaapos.2019.11.012. Epub 2020 Feb 25.

Abstract

An 18-year-old man with primary congenital glaucoma and buphthalmos in both eyes presented with unilateral, sudden-onset, painless vision loss. He had previously undergone multiple sectoral ab externo rigid-probe trabeculotomy in both eyes and subsequently Baervelt glaucoma implantion in both eyes, with adequate intraocular pressure control. Examination revealed subfoveal choroidal neovascular membrane (CNVM) and associated hemorrhages in the right eye. He was treated with 3 consecutive, monthly, intravitreal injections of bevacizumab and recovered baseline vision.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Angiogenesis Inhibitors / administration & dosage
  • Bevacizumab / administration & dosage
  • Choroid / diagnostic imaging*
  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology*
  • Fluorescein Angiography
  • Fundus Oculi
  • Glaucoma / complications
  • Glaucoma / congenital*
  • Glaucoma / diagnosis
  • Glaucoma / physiopathology
  • Humans
  • Hydrophthalmos / complications*
  • Hydrophthalmos / diagnosis
  • Intraocular Pressure / physiology*
  • Intravitreal Injections
  • Male
  • Tomography, Optical Coherence
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors
  • Visual Acuity*

Substances

  • Angiogenesis Inhibitors
  • Vascular Endothelial Growth Factor A
  • Bevacizumab

Supplementary concepts

  • Glaucoma 3, Primary Congenital, A