Identifying Vaccine-associated Rash Illness Amidst a Large Measles Outbreak: Minnesota, 2017

Clin Infect Dis. 2020 Dec 3;71(9):e517-e519. doi: 10.1093/cid/ciaa168.

Abstract

Characteristics of vaccine-associated rash illness (VARI) and confirmed measles cases were compared during a measles outbreak. Although some clinical differences were noted, measles exposure and identification of the vaccine strain were helpful for public health decision-making. Rapid, vaccine strain-specific diagnostic assays will more efficiently distinguish VARI from measles.

Keywords: genotype; measles; outbreak; rash; vaccine.

MeSH terms

  • Disease Outbreaks
  • Exanthema* / epidemiology
  • Exanthema* / etiology
  • Humans
  • Infant
  • Measles Vaccine / adverse effects
  • Measles* / diagnosis
  • Measles* / epidemiology
  • Measles* / prevention & control
  • Measles-Mumps-Rubella Vaccine / adverse effects
  • Minnesota / epidemiology
  • Vaccination

Substances

  • Measles Vaccine
  • Measles-Mumps-Rubella Vaccine