Right ventricular outflow tract prestenting with AndraStent XXL before percutaneous pulmonary valve implantation

Arch Cardiovasc Dis. 2020 Feb;113(2):113-120. doi: 10.1016/j.acvd.2019.12.004. Epub 2020 Feb 18.

Abstract

Background: The indications for percutaneous pulmonary valve implantation (PPVI) have been extended to include large dysfunctional right ventricular outflow tracts (RVOTs). Prestenting of the RVOT is commonly performed before PPVI in order to ensure a stable landing zone. The AndraStent XXL (AndraMed GmbH, Reutlingen, Germany), a cobalt-chromium stent with semi-open cell design, has unique mechanical properties in this indication but is no longer available in France.

Aims: To assess the efficiency of AndraStent XXL before PPVI.

Methods: In this retrospective multicentre cohort study, 86 AndraStents XXL were implanted in 77 patients in 6 centres.

Results: PPVI was indicated mainly for pulmonary regurgitation (75.3%) in native or patched RVOT (88.3%). The stents were manually mounted on balloon catheters and delivered through sheaths using a conventional femoral approach. PPVI was performed successfully in 97.4% of patients after successful prestenting, generally during the same procedure (77.9%). There were no deaths associated with stent implantation, and four patients experienced five complications, mainly stent embolization, including one requiring surgery. Neither stent fracture nor dysfunction were observed in any patient during a mean follow-up of 19.2±8.7months. Stent analysis showed an excellent maximal stent expansion (97.1%) regardless of balloon size. A 22.3%±3.4 stent shortening with a 30mm balloon was observed.

Conclusions: Implantation of large cobalt-chromium AndraStent XXL stents is efficient for prestenting before PPVI.

Keywords: Endoprothèse; Implantation percutanée de valve pulmonaire; Percutaneous pulmonary valve implantation; Right ventricular outflow tract; Stent; Voie de sortie ventriculaire droite.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / instrumentation*
  • Child
  • Female
  • France
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Pulmonary Valve / diagnostic imaging
  • Pulmonary Valve / physiopathology
  • Pulmonary Valve / surgery*
  • Pulmonary Valve Insufficiency / diagnostic imaging
  • Pulmonary Valve Insufficiency / physiopathology
  • Pulmonary Valve Insufficiency / surgery*
  • Recovery of Function
  • Retrospective Studies
  • Stents*
  • Treatment Outcome
  • Ventricular Outflow Obstruction / diagnostic imaging
  • Ventricular Outflow Obstruction / physiopathology
  • Ventricular Outflow Obstruction / therapy*
  • Young Adult