Infant Hospitalizations and Fatalities Averted by the Maternal Pertussis Vaccination Program in England, 2012-2017: Post-implementation Economic Evaluation

Clin Infect Dis. 2020 Nov 5;71(8):1984-1987. doi: 10.1093/cid/ciaa165.

Abstract

In October 2012, a maternal pertussis vaccination program was implemented in England following an increased incidence and mortality in infants. We evaluated the cost-effectiveness of the program by comparing pertussis-related infant hospitalizations and deaths in 2012-2017 with nonvaccination scenarios. Despite considerable uncertainties, findings support the cost-effectiveness of the program.

Keywords: economic evaluation; maternal pertussis vaccination; pertussis vaccine; postimplementation; whooping cough.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cost-Benefit Analysis
  • England / epidemiology
  • Hospitalization
  • Humans
  • Infant
  • Pertussis Vaccine
  • Vaccination
  • Whooping Cough* / epidemiology
  • Whooping Cough* / prevention & control

Substances

  • Pertussis Vaccine