Identification and characterization of a novel rhabdovirus infecting peach in China

Virus Res. 2020 Apr 15:280:197905. doi: 10.1016/j.virusres.2020.197905. Epub 2020 Feb 24.

Abstract

A novel negative-sense, single-stranded (ss) RNA virus was identified in peach trees by high-throughput sequencing, and named peach virus 1 (PeV1). The genome of PeV1 consists of 13,949 nucleotides (nt), and its organization is typical of rhabdoviruses with six open reading frames (ORFs) encoding deduced proteins N-P-P3-M-G-L on the antisense strand. These ORFs are separated by highly conserved intergenic sequences and flanked by complementary 3'-leader and 5'-trailer sequences. PeV1 shared highest complete genome (41.9%), N amino acid (43.6%), G amino acid (41.0%), and L amino acid (42.7%) identities with viruses which belong to the genus Alphanucleorhabdovirus, suggesting it may belong to a new species. This was further supported by phylogenetic analyses using amino acid sequences of N, G, and L proteins, in which this virus is always clustered with alphanucleorhabdoviruses. Collectively, results suggest that PeV1 is a member of a new alphanucleorhabdovirus species. Moreover, bioassays revealed that it could be transmitted through grafting. The findings expand our knowledge of peach-infecting viruses and alphanucleorhabdoviruses.

Keywords: Alphanucleorhabdovirus; Negative single-stranded RNA virus; Peach; Peach virus 1; RNA-Seq.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genome, Viral
  • High-Throughput Nucleotide Sequencing
  • Open Reading Frames
  • Phylogeny
  • Plant Diseases / virology*
  • Prunus persica / virology*
  • RNA, Viral / genetics
  • Rhabdoviridae / classification
  • Rhabdoviridae / genetics*
  • Rhabdoviridae / isolation & purification*
  • Sequence Analysis, DNA
  • Viral Proteins / genetics

Substances

  • RNA, Viral
  • Viral Proteins