Past, present and future of adjuvant HIPEC in patients at high risk for colorectal peritoneal metastases

Affiliations

• ¹ Peritoneal Malignancy Program, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian, 1, 20133, Milan, Italy. Electronic address: [email protected].
• ² Cytoreductive Surgery and HIPEC Unit, Department of Surgery "Pietro Valdoni", Azienda Policlinico Umberto I, Sapienza University, Viale del Policlinico, 155, 00161, Rome, Italy.
• ³ Peritoneal Malignancy Program, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian, 1, 20133, Milan, Italy.
• ⁴ Department of Surgery, General and Emergency Surgery Unit, Bufalini Hospital, Cesena, Italy.
• ⁵ Division of Surgical Oncology, Ascoli Tomaselli Hospital, Catania, Italy.
• ⁶ Department of General Surgery, Spedali Civili di Brescia, Brescia, Italy.
• ⁷ Emergency and General Surgery Unit, Istituto Clinico Città di Milano, Milano, Italy.
• ⁸ General Surgery and Surgical Oncology Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
• ⁹ General and Oncological Surgery Unit, University of Perugia, Terni, Italy.
• ¹⁰ Department of General, Emergency and Trauma Surgery, Papa Giovanni XXIII Hospital, Bergamo, Italy.
• ¹¹ Department of General Surgery, Policlinico San Martino, University of Genoa, Genoa, Italy.
• ¹² Abdominal Oncology Department, Fondazione Giovanni Pascale, IRCCS, Naples, Italy.
• ¹³ Department of Surgical Oncology, Candiolo Institute for Cancer Research and Treatment, Torino, Italy.
• ¹⁴ Division of General Surgery, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
• ¹⁵ Department of Obstetrics and Gynecology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Catholic University of the Sacred Heart, Rome, Italy.
• ¹⁶ Department of Surgery, Surgical Oncology, National Cancer Institute Regina Elena, Rome, Italy.
• ¹⁷ Department of Oncology and Hematology, Ospedali Riuniti Marche Nord, Pesaro, Italy.
• ¹⁸ Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy.
• ¹⁹ Department of Digestive Surgery, Regina Elena National Cancer Institute, IRCCS-IFO, Rome, Italy.
• ²⁰ Department of Surgery, Policlinico of Modena, University of Modena and Reggio Emilia, Modena, Italy.
• ²¹ Department of General and Emergency Surgery, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.
• ²² Peritoneal Malignancy Program, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
• ²³ Department of Surgery, Azienda Ospedaliero Universitaria Pisana (AOUP), S.D. General and Peritoneal Surgery, Pisa, Italy.
• ²⁴ Department of Surgery, Peritoneal Surface Malignancy and Soft Tissue Sarcoma Program, University of Messina, Italy.
• ²⁵ Department of Surgery, AOU Santa Maria della Misericordia, Udine, Italy.
• ²⁶ Department of Medical, Surgical and Neuroscience, University of Siena, Siena, Italy.
• ²⁷ Department of Surgery, San Raffaele Scientific Institute, Milan, Italy.
• ²⁸ Unit of Surgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.