Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8

Acta Neuropathol. 2020 Jun;139(6):1115-1118. doi: 10.1007/s00401-020-02139-5. Epub 2020 Mar 2.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / genetics*
  • DEAD-box RNA Helicases / genetics*
  • Humans
  • Pineal Gland / metabolism
  • Pinealoma / genetics*
  • Pinealoma / pathology
  • RNA-Binding Proteins / genetics*
  • RNA-Binding Proteins / metabolism
  • Ribonuclease III / genetics*

Substances

  • DGCR8 protein, human
  • RNA-Binding Proteins
  • DICER1 protein, human
  • DROSHA protein, human
  • Ribonuclease III
  • DEAD-box RNA Helicases