Diagnostic deep-targeted next-generation sequencing assessment of TP53 gene mutations in multiple myeloma from the whole bone marrow

Br J Haematol. 2020 May;189(4):e122-e125. doi: 10.1111/bjh.16547. Epub 2020 Mar 4.
No abstract available

Keywords: disruption of tumour protein p53 (TP53) gene; multiple myeloma; mutation; next-generation sequencing; plasma cell enrichment.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Marrow / pathology*
  • Female
  • Genes, p53*
  • High-Throughput Nucleotide Sequencing / methods
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma / genetics*
  • Multiple Myeloma / pathology
  • Mutation*
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53