Disseminated cytomegalovirus infection with bilateral adrenal pseudotumors masquerading as recurrent hematologic malignancy

Nicolo L Cabrera; Alexandre E Malek; Samuel Shelburne; Mahnaz Taremi; Hesham Awadh; Denise Francisco; Alison Robins; Elias Jabbour; Roy F Chemaly

doi:10.1007/s15010-020-01404-9

Disseminated cytomegalovirus infection with bilateral adrenal pseudotumors masquerading as recurrent hematologic malignancy

Infection. 2020 Jun;48(3):477-481. doi: 10.1007/s15010-020-01404-9. Epub 2020 Mar 6.

Authors

Nicolo L Cabrera^{1

2}, Alexandre E Malek^{3

4}, Samuel Shelburne³, Mahnaz Taremi³, Hesham Awadh^{3

4}, Denise Francisco^{3

5}, Alison Robins^{3

5}, Elias Jabbour⁶, Roy F Chemaly³

Affiliations

¹ Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. [email protected].
² Division of Infectious Diseases, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, 6431 Fannin St., Houston, TX, 77030, USA. [email protected].
³ Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
⁴ Division of Infectious Diseases, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, 6431 Fannin St., Houston, TX, 77030, USA.
⁵ Department of Infectious Diseases, Baylor College of Medicine, 7200 Cambridge St., Houston, TX, 77030, USA.
⁶ Department of Leukemia, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.

PMID: 32144592
DOI: 10.1007/s15010-020-01404-9

Abstract

Background: Mass-like lesions are an uncommon presentation of cytomegalovirus (CMV) disease.

Case: We report on a case of disseminated CMV disease with bilateral adrenal pseudotumors in a patient with a history of acute leukemia in remission.

Conclusion: In the settings of advanced cancer therapy and organ transplantation, a high index of suspicion for CMV should be maintained for mass-like disease.

Keywords: Adrenal gland; Cytomegalovirus; Disseminated infection; Hematologic malignancy; Pseudotumor.

Publication types

Case Reports

MeSH terms

Adrenal Gland Diseases / diagnosis*
Adrenal Gland Diseases / drug therapy
Adrenal Gland Diseases / pathology
Adrenal Gland Diseases / virology
Cytomegalovirus / physiology
Cytomegalovirus Infections / diagnosis*
Cytomegalovirus Infections / drug therapy
Cytomegalovirus Infections / pathology
Cytomegalovirus Infections / virology
Hematologic Neoplasms / pathology
Hematologic Neoplasms / virology
Humans
Male
Middle Aged
Recurrence
Texas
Treatment Outcome