Loss of Filamin C Is Catastrophic for Heart Function

Circulation. 2020 Mar 10;141(10):869-871. doi: 10.1161/CIRCULATIONAHA.119.044061. Epub 2020 Mar 9.
No abstract available

Keywords: cardiomyopathy; filamins; mutation; myocytes, cardiac.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cardiomyopathy, Dilated / genetics*
  • Cells, Cultured
  • Disease Models, Animal
  • Fibrosis / genetics
  • Filamins / genetics
  • Filamins / metabolism*
  • Humans
  • Mice
  • Mice, Knockout
  • Muscle Development / genetics*
  • Muscle, Skeletal / physiology
  • Mutation / genetics
  • Myocardial Contraction / genetics
  • Myocardium / pathology*
  • Myocytes, Cardiac / pathology
  • Myocytes, Cardiac / physiology*

Substances

  • Filamins