Background: Verrucous or hypertrophic lichen planus is a chronic inflammatory skin disease characterized by extremely pruritic thick hyperkeratotic plaques and is resistant to topical treatment.
Patients and methods: Herein, we report three clinical cases of hypertrophic lichen planus successfully treated with a combination of topical steroids daily in occlusion and trichloroacetic acid (TCA) 50% with peeling every week.
Discussion: TCA is involved in regulating inflammation and scarring. Through its keratolytic properties it enhances the efficacy of topical steroids, whose action is hindered by hyperkeratosis.
Conclusion: The combination of TCA and topical steroids offers a good alternative for the treatment of hypertrophic lichen planus.
Keywords: Acide trichloroacétique; Dermocorticoïdes; Hypertrophic lichen planus; Lichen plan hypertrophique; Lichen plan verruqueux; Topical steroids; Trichloroacetic acid; Verrucous lichen planus.
Copyright © 2019. Published by Elsevier Masson SAS.