Recent advances in the chemical synthesis of insulin and related peptides

Future Med Chem. 2020 Apr;12(8):649-654. doi: 10.4155/fmc-2020-0013. Epub 2020 Mar 17.

Authors

Florence M Brunel¹, John P Mayer², Richard D DiMarchi^{1

3}

Affiliations

¹ Department of Chemistry, Novo Nordisk Research Center, Indianapolis, IN 46241, USA.
² Molecular, Cellular & Developmental Biology, University of Colorado, Boulder, CO 80309, USA.
³ Department of Chemistry, Indiana University, Bloomington, IN 47405, USA.

PMID: 32180453
DOI: 10.4155/fmc-2020-0013

No abstract available

Keywords: chain combination; chemical synthesis; directed oxidation; insulin; single-chain precursor.

Publication types

Editorial
Review

MeSH terms

Insulin / chemical synthesis*
Insulin / chemistry
Peptides / chemical synthesis*
Peptides / chemistry

Substances

Insulin
Peptides