Macular imaging with optical coherence tomography in glaucoma

Vahid Mohammadzadeh; Nima Fatehi; Adeleh Yarmohammadi; Ji Woong Lee; Farideh Sharifipour; Ramin Daneshvar; Joseph Caprioli; Kouros Nouri-Mahdavi

doi:10.1016/j.survophthal.2020.03.002

Macular imaging with optical coherence tomography in glaucoma

Surv Ophthalmol. 2020 Nov-Dec;65(6):597-638. doi: 10.1016/j.survophthal.2020.03.002. Epub 2020 Mar 19.

Authors

Vahid Mohammadzadeh¹, Nima Fatehi², Adeleh Yarmohammadi³, Ji Woong Lee⁴, Farideh Sharifipour⁵, Ramin Daneshvar⁶, Joseph Caprioli¹, Kouros Nouri-Mahdavi⁷

Affiliations

¹ Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA.
² Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA; Saint Mary Medical Center - Dignity Health, Long Beach, California, USA.
³ Shiley Eye Institute, University of California, San Diego, La Jolla, California, United States.
⁴ Department of Ophthalmology, Pusan National University College of Medicine, Busan, Korea.
⁵ Department of Ophthalmology, Shahid Beheshti university of Medical Sciences, Tehran, Iran.
⁶ Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
⁷ Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA. Electronic address: [email protected].

Abstract

With the advent of spectral-domain optical coherence tomography, imaging of the posterior segment of the eye can be carried out rapidly at multiple anatomical locations, including the optic nerve head, circumpapillary retinal nerve fiber layer, and macula. There is now ample evidence to support the role of spectral-domain optical coherence tomography imaging of the macula for detection of early glaucoma. Macular spectral-domain optical coherence tomography measurements demonstrate high reproducibility, and evidence on its utility for detection of glaucoma progression is accumulating. We present a comprehensive review of macular spectral-domain optical coherence tomography imaging emerging as an essential diagnostic tool in glaucoma.

Keywords: OCT; detection; glaucoma; imaging; macula; optical coherence tomography; progression; structure-function; variability.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Glaucoma / diagnosis*
Humans
Macula Lutea / pathology*
Reproducibility of Results
Retinal Ganglion Cells / pathology
Tomography, Optical Coherence / methods*

Grants and funding

R01 EY029792/EY/NEI NIH HHS/United States