Outcomes of Transperineal Gender-Affirming Vaginectomy and Colpocleisis

Female Pelvic Med Reconstr Surg. 2021 May 1;27(5):300-303. doi: 10.1097/SPV.0000000000000843.

Abstract

Objectives: There are multiple approaches to vaginectomy for the purpose of masculinizing gender-affirming genital surgery including mucosal fulguration and excision. The outcomes of the approaches are not well described. We aim to describe the surgical outcomes of gender-affirming vaginectomy and colpocleisis by complete mucosal excision.

Methods: We performed a case series study of 40 transmasculine patients who underwent gender-affirming vaginectomy and colpocleisis. Vaginectomy was performed by complete excision of the vaginal mucosa via a transperineal approach. We recorded perioperative outcomes and operative time. We performed a multivariate analysis to assess patient factors on operative outcomes.

Results: Forty vaginectomies were performed between September 2016 and April 2019, 27 (67.5%) in phalloplasty patients and 13 (32.5%) in metoidioplasty patients. Perioperative complications included 2 blood transfusions, 1 pelvic hematoma, and 1 Clostridium cifficile colitis. No urethral fistulae to the vaginal space, mucoceles, or visceral injures were seen with a median follow-up of 7.7 months. Operative time decreased significantly with later surgery year.

Conclusions: This is a large series studying the outcomes of gender-affirming vaginectomy by complete mucosal excision approach in the literature. Perioperative complications were low. Operative time decreased overtime such that after approximately 20 cases, the procedure fairly consistently takes 2 to 2.5 hours to perform.

MeSH terms

  • Adult
  • Colpotomy*
  • Female
  • Gender-Affirming Surgery / methods*
  • Humans
  • Male
  • Middle Aged
  • Perineum
  • Retrospective Studies
  • Treatment Outcome
  • Vagina / surgery*