High FDG Uptake in Pleomorphic Hyalinizing Angiectatic Tumor

Clin Nucl Med. 2020 May;45(5):407-409. doi: 10.1097/RLU.0000000000003001.

Abstract

PHAT (pleomorphic hyalinizing angiectatic tumor) is a rare, locally aggressive, low-grade mesenchymal neoplasm of uncertain lineage with a predilection for the lower extremities. We report a 74-year-old woman with an enlarging mass on the right popliteal fossa undergoing FDG PET/CT to characterize its biological activity. Increased accumulation of FDG (SUVmax, 23.0) in the solid component of the tumor was seen. Diagnosis of PHAT was confirmed by examination of the surgical resection specimens. This case showed significant FDG accumulation relative to its pathological low-grade malignant nature.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biological Transport
  • Female
  • Fluorodeoxyglucose F18 / metabolism*
  • Humans
  • Positron Emission Tomography Computed Tomography
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / metabolism*
  • Soft Tissue Neoplasms / pathology

Substances

  • Fluorodeoxyglucose F18