18F-PSMA 1007 in Suspected Renal Cell Carcinoma

Clin Nucl Med. 2020 May;45(5):377-378. doi: 10.1097/RLU.0000000000003002.

Abstract

A 60-year-old man with suspected right renal cell carcinoma underwent F-FDG PET/CT and F prostate-specific membrane antigen (PSMA) 1007 PET/CT scan. Compared with the F-FDG PET/CT scan, F-PSMA 1007 PET/CT showed intense tracer concentration in the primary tumor in the right kidney and intense tracer concentration consistently in all lung nodules. Unlike noted in previous pilot studies with Ga-PSMA, we observed that the primary renal tumor also showed intense tracer avidity with F-PSMA 1007. F-PSMA 1007 PET/CT may provide preoperative insight into possible etiology, histopathological probability of tumor type, staging information, and theranostic potentials in evaluation of suspected renal cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Renal Cell / diagnostic imaging*
  • Fluorine Radioisotopes
  • Humans
  • Kidney Neoplasms / diagnostic imaging*
  • Male
  • Middle Aged
  • Niacinamide / analogs & derivatives
  • Oligopeptides
  • Positron Emission Tomography Computed Tomography / methods*
  • Radiopharmaceuticals

Substances

  • Fluorine Radioisotopes
  • Oligopeptides
  • PSMA-1007
  • Radiopharmaceuticals
  • Niacinamide