Successful Lung Transplantation After Acellular Ex Vivo Lung Perfusion With Prone Positioning

Hiromichi Niikawa; Toshihiro Okamoto; Kamal S Ayyat; Ichiro Sakanoue; James J Yun; Kenneth R McCurry

doi:10.1016/j.athoracsur.2020.02.045

Successful Lung Transplantation After Acellular Ex Vivo Lung Perfusion With Prone Positioning

Ann Thorac Surg. 2020 Oct;110(4):e285-e287. doi: 10.1016/j.athoracsur.2020.02.045. Epub 2020 Mar 27.

Authors

Hiromichi Niikawa¹, Toshihiro Okamoto², Kamal S Ayyat¹, Ichiro Sakanoue¹, James J Yun², Kenneth R McCurry³

Affiliations

¹ Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
² Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio; Transplant Center, Cleveland Clinic, Cleveland, Ohio.
³ Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio; Transplant Center, Cleveland Clinic, Cleveland, Ohio. Electronic address: [email protected].

PMID: 32224244
DOI: 10.1016/j.athoracsur.2020.02.045

Abstract

Use of prone positioning during ex vivo lung perfusion (EVLP) with the Toronto protocol reduced pulmonary edema in marginal human donor lungs. This report describes 2 cases in which prone positioning during EVLP significantly reduced lung weight. One of the 2 cases resulted in successful double-lung transplantation.

Publication types

Case Reports

MeSH terms

Humans
Lung / physiology*
Lung / surgery*
Lung Transplantation / methods*
Male
Middle Aged
Perfusion / methods*
Preoperative Care / methods*
Prone Position
Treatment Outcome
Young Adult