Thymoquinone as a causative allergen in Nigella sativa oil contact dermatitis with cross-reactivity to tert-butylhydroquinone

Contact Dermatitis. 2020 Aug;83(2):132-134. doi: 10.1111/cod.13542. Epub 2020 May 7.

Authors

Flore Kurihara¹, Angele Soria^{1

2}, Jean-Pierre Lepoittevin³, Francois Chasset¹, Annick Barbaud^{1

4}, Catherine Pecquet¹

Affiliations

¹ Tenon Hospital, Dermatology-Allergology, Sorbonne University, Paris, France.
² Immunology and Infectious Diseases Center-Paris(Cimi-Paris)-INSERM U1135, Paris, France.
³ Laboratory of Dermatochimie, Institute of Chemistry, CNRS and University of Strasbourg, Strasbourg, France.
⁴ Pierre Louis Institute of Epidemiology and Public Health, AP-HP.Sorbonne University, Paris, France.

PMID: 32232855
DOI: 10.1111/cod.13542

No abstract available

Keywords: Nigella sativa oil; allergic contact dermatitis; alternative medicine; black cumin; essential oil; t-butylhydroquinone; thymoquinone.

Publication types

Case Reports

MeSH terms

Allergens / adverse effects
Alopecia / drug therapy
Benzoquinones / adverse effects*
Benzoquinones / immunology
Cross Reactions / immunology
Dermatitis, Allergic Contact / etiology*
Dermatitis, Allergic Contact / immunology
Facial Dermatoses / chemically induced
Female
Humans
Hydroquinones / immunology
Middle Aged
Nigella sativa
Plant Oils / adverse effects*
Scalp Dermatoses / chemically induced

Substances

Allergens
Benzoquinones
Hydroquinones
Plant Oils
2-tert-butylhydroquinone
thymoquinone