The emergence of regenerative medicine in organ transplantation: 1st European Cell Therapy and Organ Regeneration Section meeting

Martin J Hoogduijn; Nuria Montserrat; Luc J W van der Laan; Francesco Dazzi; Norberto Perico; Jens Kastrup; Nicholas Gilbo; Rutger J Ploeg; Valerie Roobrouck; Federica Casiraghi; Christian L Johnson; Marcella Franquesa; Marc H Dahlke; Emma Massey; Sarah Hosgood; Marlies E J Reinders

doi:10.1111/tri.13608

The emergence of regenerative medicine in organ transplantation: 1st European Cell Therapy and Organ Regeneration Section meeting

Transpl Int. 2020 Aug;33(8):833-840. doi: 10.1111/tri.13608. Epub 2020 Apr 28.

Authors

Martin J Hoogduijn¹, Nuria Montserrat^{2

3

4}, Luc J W van der Laan⁵, Francesco Dazzi⁶, Norberto Perico⁷, Jens Kastrup⁸, Nicholas Gilbo^{9

10}, Rutger J Ploeg¹¹, Valerie Roobrouck¹², Federica Casiraghi⁷, Christian L Johnson¹³, Marcella Franquesa¹⁴, Marc H Dahlke¹⁵, Emma Massey¹, Sarah Hosgood¹⁶, Marlies E J Reinders¹⁷

Affiliations

¹ Department of Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
² Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Technology (BIST), Barcelona, Spain.
³ Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
⁴ Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Madrid, Spain.
⁵ Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
⁶ School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.
⁷ Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
⁸ Cardiology Stem Cell Center, Rigshospitalet University Hospital Copenhagen, Copenhagen, Denmark.
⁹ Lab of Abdominal Transplantation, Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
¹⁰ Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
¹¹ Nuffield Department of Surgical Sciences and Oxford Transplant Centre, University of Oxford and Oxford University Hospitals NHS Trust, Oxford, UK.
¹² Regenesys/Athersys, Leuven, Belgium.
¹³ Institute for Clinical Chemistry and Laboratory Medicine, Transfusion Medicine, University Hospital Regensburg, Regensburg, Germany.
¹⁴ REMAR-IVECAT Group, Germans Trias i Pujol Health Science Research Institute, Badalona, Spain.
¹⁵ Department of Surgery, Robert-Bosch-Health-Campus, Stuttgart, Germany.
¹⁶ Department of Surgery, University of Cambridge, Cambridge, UK.
¹⁷ Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands.

Abstract

Regenerative medicine is emerging as a novel field in organ transplantation. In September 2019, the European Cell Therapy and Organ Regeneration Section (ECTORS) of the European Society for Organ Transplantation (ESOT) held its first meeting to discuss the state-of-the-art of regenerative medicine in organ transplantation. The present article highlights the key areas of interest and major advances in this multidisciplinary field in organ regeneration and discusses its implications for the future of organ transplantation.

Keywords: cell therapy; machine perfusion; mesenchymal stromal cell; organoid; regeneration; transplantation.

Publication types

Review

MeSH terms

Cell- and Tissue-Based Therapy
Organ Transplantation*
Regeneration
Regenerative Medicine*