Allergic bronchopulmonary aspergillosis without asthma or cystic fibrosis

Paediatr Int Child Health. 2020 Aug;40(3):199-201. doi: 10.1080/20469047.2020.1744872. Epub 2020 Apr 2.

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an immunological disease complicating asthma or cystic fibrosis. An 8-year-old girl with no previous respiratory morbidity was diagnosed with ABPA on the basis of a raised eosinophil count and total and specific serum IgE levels combined with a positive skin-prick test for aspergillus and typical CT images of finger-in-glove hilar opacities and hyperattenuating mucous. She responded to treatment with itraconazole and corticosteroids and remains well. As far as we are aware, she is only the second child to be diagnosed with ABPA without asthma or cystic fibrosis.

Keywords: ABPA; ABPM; aspergillosis; aspergillus; bronchiectasis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Aspergillosis, Allergic Bronchopulmonary / diagnosis*
  • Aspergillosis, Allergic Bronchopulmonary / drug therapy
  • Aspergillosis, Allergic Bronchopulmonary / pathology*
  • Child
  • Female
  • Humans
  • Immunoglobulin E / blood
  • Itraconazole / therapeutic use
  • Prednisolone / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Antifungal Agents
  • Itraconazole
  • Immunoglobulin E
  • Prednisolone