The efficacy of transdermal and oral diclofenac for post-endodontic pain control: A randomised controlled trial

Indian J Dent Res. 2020 Jan-Feb;31(1):53-56. doi: 10.4103/ijdr.IJDR_167_17.

Abstract

Objective: The aim of the present study was to compare the effect of transdermal diclofenac patch against oral diclofenac for post-endodontic pain control.

Materials and methods: Thirty-two patients with symptomatic irreversible pulpitis in single-rooted premolar teeth of either arch were treated endodontically in a single visit by a single endodontist. Oral diclofenac (50 mg twice daily) for group I and transdermal diclofenac patch (100 mg once daily) for group II were administered as post-endodontic analgesics for two days. Visual analogue scale (VAS) chart was used to record pain intensity scores preoperatively and at intervals of 4, 8, 12 and 24 h postoperatively for 2 days. Paracetamol 650 mg tablets were provided as rescue medication.

Results: There was a significant decrease in the postoperative pain intensity scores for both groups. The postoperative scores gradually decreased from day 1 to day 2 in both groups. Twelve out of sixteen patients who had received diclofenac tablets complained of gastric discomfort.

Conclusion: Transdermal diclofenac patch was as effective as an oral diclofenac tablet and can be used as an alternative and effective analgesic for post-endodontic pain management, especially in patients with gastric discomfort.

Keywords: Diclofenac; post-endodontic pain; transdermal patch.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acetaminophen
  • Administration, Cutaneous
  • Analgesics*
  • Anti-Inflammatory Agents, Non-Steroidal
  • Diclofenac*
  • Double-Blind Method
  • Humans
  • Pain, Postoperative

Substances

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Diclofenac
  • Acetaminophen