Synergistic interaction between thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide and sorafenib in liver cancer cells

Hepatobiliary Pancreat Dis Int. 2020 Jun;19(3):295-298. doi: 10.1016/j.hbpd.2020.03.003. Epub 2020 Mar 19.
No abstract available

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Carcinoma, Hepatocellular / drug therapy*
  • Cell Line, Tumor
  • Cell Survival / drug effects*
  • Disulfides / pharmacology*
  • Drug Synergism
  • Humans
  • Imidazoles / pharmacology*
  • Inhibitory Concentration 50
  • Liver Neoplasms / drug therapy*
  • Sorafenib / pharmacology*
  • Thioredoxins / antagonists & inhibitors

Substances

  • Antineoplastic Agents
  • Disulfides
  • Imidazoles
  • TXN protein, human
  • Thioredoxins
  • 1-methylpropyl-2-imidazolyl disulfide
  • Sorafenib