Zirconia-doped nanoparticles: organic coating, polymeric entrapment and application as dual-imaging agents

J Mater Chem B. 2013 Feb 21;1(7):919-923. doi: 10.1039/c2tb00208f. Epub 2013 Jan 9.

Abstract

Zirconia nanoparticles doped with Eu3+, Tb3+ and Gd3+ ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were investigated, proving them to be potential dual-imaging contrast agents.