Abstract
We saw a 59-year-old patient who was treated with dabrafenib and trametinib because of metastatic melanoma. She had an asymptomatic, black-blue macula in the excision scar. Histopathology showed tumoral melanosis. This is an histological term for dermal aggregates of melanophages, associated with regression of melanoma.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols
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Cicatrix / diagnosis
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Female
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Humans
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Imidazoles / therapeutic use*
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Melanoma / drug therapy*
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Melanoma / pathology
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Melanosis / pathology
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Middle Aged
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Oximes / therapeutic use*
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Pyridones / therapeutic use*
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Pyrimidinones / therapeutic use*
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Skin Diseases / etiology
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Skin Neoplasms / drug therapy*
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Skin Neoplasms / pathology
Substances
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Imidazoles
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Oximes
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Pyridones
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Pyrimidinones
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trametinib
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dabrafenib