Identification of a novel HLA-DQB105 variant allele, HLA-DQB105:247 by next-generation sequencing

HLA. 2020 Aug;96(2):242-243. doi: 10.1111/tan.13896. Epub 2020 Apr 26.

Authors

Shinae Yu¹, Hae Jung Bae¹, So-Jung Choi², Kyung Ran Jun¹

Affiliations

¹ Department of Laboratory Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
² Dow Biomedica Inc., Seoul, South Korea.

PMID: 32276294
DOI: 10.1111/tan.13896

Abstract

The new allele, HLA-DQB1*05:247 differs from HLA-DQB1*05:02:01:01 by one nucleotide substitution at codon 35.

Keywords: HLA-DQB1*05:247; HLA; new allele; next-generation sequencing; novel allele.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Exons / genetics
HLA-DQ beta-Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen