Merkel cell carcinoma of lymph nodes without a skin primary tumor: A potential metastatic neoplasia associated with a brisk immune response

Thibault Kervarrec; Julia Zaragoza; Pauline Gaboriaud; Patricia Berthon; Gaelle Fromont; Yannick Le Corre; Eva Hainaut-Wierzbicka; Francois Aubin; Guido Bens; Patrick Michenet; Hervé Maillard; Roland Houben; David Schrama; Agnes Caille; Antoine Touzé; Serge Guyétant; Mahtab Samimi

doi:10.1016/j.jaad.2020.03.108

Merkel cell carcinoma of lymph nodes without a skin primary tumor: A potential metastatic neoplasia associated with a brisk immune response

J Am Acad Dermatol. 2020 Dec;83(6):1789-1792. doi: 10.1016/j.jaad.2020.03.108. Epub 2020 Apr 9.

Authors

Thibault Kervarrec¹, Julia Zaragoza², Pauline Gaboriaud³, Patricia Berthon³, Gaelle Fromont⁴, Yannick Le Corre⁵, Eva Hainaut-Wierzbicka⁶, Francois Aubin⁷, Guido Bens², Patrick Michenet⁸, Hervé Maillard⁹, Roland Houben¹⁰, David Schrama¹⁰, Agnes Caille¹¹, Antoine Touzé³, Serge Guyétant¹², Mahtab Samimi¹³

Affiliations

¹ Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Chambray-les-tours, France; UMR INRA ISP 1282, team "Biologie des infections à polyomavirus", Université de Tours, Faculté des Sciences Pharmaceutiques 31, France. Electronic address: [email protected].
² Dermatology Department, Centre Hospitalier Régional d'Orléans, France.
³ UMR INRA ISP 1282, team "Biologie des infections à polyomavirus", Université de Tours, Faculté des Sciences Pharmaceutiques 31, France.
⁴ Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, France.
⁵ Dermatology Department, Université Nantes-Angers-Le Mans, Centre Hospitalier Universitaire Angers, France.
⁶ Dermatology Department, Université de Poitiers, Centre Hospitalier Universitaire de Poitiers, France.
⁷ Dermatology Department, Université de Franche Comté, Centre Hospitalier Universitaire Besançon, France.
⁸ Department of Pathology, Centre Hospitalier Régional d'Orléans, France.
⁹ Dermatology Department, Centre Hospitalier Régional Le Mans, France.
¹⁰ Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Germany.
¹¹ Clinical Investigation Center, INSERM CIC 1415, University Hospital of Tours, France; Université de Tours, Université de Nantes, INSERM U1246-SPHERE, France.
¹² Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Chambray-les-tours, France; UMR INRA ISP 1282, team "Biologie des infections à polyomavirus", Université de Tours, Faculté des Sciences Pharmaceutiques 31, France.
¹³ Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Chambray-les-tours, France; Dermatology Department, Université Francois Rabelais, Centre Hospitalier Universitaire de Tours, Chambray-les-tours, France.

PMID: 32278804
DOI: 10.1016/j.jaad.2020.03.108

No abstract available

Publication types

Letter

MeSH terms

Biomarkers, Tumor / analysis
Carcinoma, Merkel Cell / diagnosis*
Carcinoma, Merkel Cell / secondary
Carcinoma, Merkel Cell / virology
Humans
Lymph Nodes / pathology*
Lymph Nodes / virology
Lymphatic Metastasis / diagnosis*
Lymphatic Metastasis / pathology
Merkel cell polyomavirus / isolation & purification
Neoplasms, Unknown Primary / diagnosis*
Neoplasms, Unknown Primary / virology
Skin Neoplasms / diagnosis
Skin Neoplasms / pathology*
Skin Neoplasms / virology

Substances

Biomarkers, Tumor