Clinically significant traumatic intracranial hemorrhage following minor head trauma in older adults: a retrospective cohort study

Brain Inj. 2020 May 11;34(6):834-839. doi: 10.1080/02699052.2020.1753242. Epub 2020 Apr 14.

Abstract

Objectives: The primary objective of this study was to determine the incidence of clinically significant traumatic intracranial hemorrhage (T-ICH) following minor head trauma in older adults. Secondary objective was to investigate the impact of anticoagulant and antiplatelet therapies on T-ICH incidence.

Methods: This retrospective cohort study extracted data from electronic patient records. The cohort consisted of patients presenting after a fall and/or head injury and presented to one of five ED between 1st March 2010 and 31st July 2017. Inclusion criteria were age ≥ 65 years old and a minor head trauma defined as an impact to the head without fulfilling criteria for traumatic brain injury.

Results: From the 1,000 electronic medical records evaluated, 311 cases were included. The mean age was 80.1 (SD 7.9) years. One hundred and eighty-nine (189) patients (60.8%) were on an anticoagulant (n = 69), antiplatelet (n = 130) or both (n = 16). Twenty patients (6.4%) developed a clinically significant T-ICH. Anticoagulation and/or antiplatelets therapies were not associated with an increased risk of clinically significant T-ICH in this cohort (Odds ratio (OR) 2.7, 95% CI 0.9-8.3).

Conclusions: In this cohort of older adults presenting to the ED following minor head trauma, the incidence of clinically significant T-ICH was 6.4%.

Keywords: Falls; Trauma; anti-platelet; anticoagulant; computed tomography; head Injury; intracranial hemorrhage; traumatic brain injury.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anticoagulants / therapeutic use
  • Cohort Studies
  • Craniocerebral Trauma* / complications
  • Craniocerebral Trauma* / epidemiology
  • Humans
  • Infant, Newborn
  • Intracranial Hemorrhage, Traumatic* / epidemiology
  • Intracranial Hemorrhage, Traumatic* / etiology
  • Intracranial Hemorrhages / epidemiology
  • Intracranial Hemorrhages / etiology
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Anticoagulants