Argatroban

Argatroban is a medication used to manage heparin-induced thrombocytopenia (HIT), which is a rare, life-threatening complication of heparin therapy. It is a direct thrombin inhibitor, a class of anticoagulant drugs. This activity outlines the indications, action, and contraindications for argatroban as a valuable agent in the prophylaxis and treating thrombosis in patients with HIT. This activity also highlights the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the healthcare team in the management of patients with heparin-induced thrombocytopenia.