DNA Editing for Amyotrophic Lateral Sclerosis: Leading Off First Base

CRISPR J. 2020 Apr;3(2):75-77. doi: 10.1089/crispr.2020.29087.tcu.

Authors

Thomas J Cunningham¹, Elizabeth Fisher², Pietro Fratta², Jonathan D Gilthorpe³

Affiliations

¹ Mammalian Genetics Unit, MRC Harwell Institute, Didcot, United Kingdom.
² Department of Neuromuscular Diseases, Institute of Neurology, University College London, London, United Kingdom.
³ Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.

PMID: 32315228
DOI: 10.1089/crispr.2020.29087.tcu

No abstract available

MeSH terms

Amyotrophic Lateral Sclerosis / genetics*
Amyotrophic Lateral Sclerosis / therapy
DNA / genetics
Gene Editing / methods
Genetic Therapy / methods*
Genetic Therapy / trends
Humans
Superoxide Dismutase-1 / genetics
Superoxide Dismutase-1 / metabolism

Substances

SOD1 protein, human
DNA
Superoxide Dismutase-1

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