Characterization of the novel HLA-DRB1*15:170 allele in a French hematopoietic stem cell donor

HLA. 2020 Sep;96(3):358-359. doi: 10.1111/tan.13915. Epub 2020 May 20.

Authors

Céline Dard¹, Ornella Senoussi¹, Vincent Elsermans², Béatrice Bardy¹, Dominique Masson¹

Affiliations

¹ Department of Biology and Therapies, Histocompatibility Laboratory, Etablissement Français du sang Auvergne-Rhône-Alpes, Grenoble, France.
² Institut d'Immunologie - HLA, CHRU de Lille, Lille, France.

PMID: 32337839
DOI: 10.1111/tan.13915

Abstract

HLA-DRB1*15:170 differs from HLA-DRB1*15:01:01:03 by one nucleotide substitution at codon 85 in exon 2.

Keywords: HLA-DRB1*15:170; NGS; human leucocyte antigen; novel HLA alleles.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Case Reports

MeSH terms

Alleles
Base Sequence
HLA-DRB1 Chains / genetics
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells
Histocompatibility Testing
Sequence Alignment
Sequence Analysis, DNA

Substances

HLA-DRB1 Chains