High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients

Wenjing Wang; Bin Su; Lijun Pang; Luxin Qiao; Yingmei Feng; Yabo Ouyang; Xianghua Guo; Hongbo Shi; Feili Wei; Xiaogang Su; Jiming Yin; Ronghua Jin; Dexi Chen

doi:10.1038/s41423-020-0447-2

High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients

Cell Mol Immunol. 2020 Jun;17(6):650-652. doi: 10.1038/s41423-020-0447-2. Epub 2020 Apr 28.

Authors

Wenjing Wang^#^{1

2}, Bin Su^#³, Lijun Pang^#^{1

2}, Luxin Qiao^{1

2}, Yingmei Feng^{1

2}, Yabo Ouyang^{1

2}, Xianghua Guo^{1

2}, Hongbo Shi^{1

2}, Feili Wei^{1

2}, Xiaogang Su^{1

2}, Jiming Yin^{1

2}, Ronghua Jin^{4

5}, Dexi Chen^{6

7}

Affiliations

¹ Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, 100069, Beijing, China.
² Beijing Precision Medicine and Transformation Engineering Technology Research Center of Hepatitis and Liver Cancer, 100069, Beijing, China.
³ Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, 100069, Beijing, China.
⁴ Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, 100069, Beijing, China. [email protected].
⁵ Beijing Precision Medicine and Transformation Engineering Technology Research Center of Hepatitis and Liver Cancer, 100069, Beijing, China. [email protected].
⁶ Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, 100069, Beijing, China. [email protected].
⁷ Beijing Precision Medicine and Transformation Engineering Technology Research Center of Hepatitis and Liver Cancer, 100069, Beijing, China. [email protected].

^# Contributed equally.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

COVID-19
Coronavirus Infections / immunology*
Female
Flow Cytometry
Humans
Immunocompromised Host
Leukocytes, Mononuclear / immunology
Male
Mass Spectrometry
Middle Aged
Pandemics
Pneumonia, Viral / immunology*

Publication types

MeSH terms

Grants and funding