Transcatheter aortic valve replacement (TAVR) as bridge therapy restoring eligibility for liver transplantation in cirrhotic patients

Am J Transplant. 2020 Sep;20(9):2567-2570. doi: 10.1111/ajt.15955. Epub 2020 Jul 8.

Abstract

Severe aortic stenosis is a widespread valve disease, constituting a contraindication to organ transplantation due to cardiovascular morbidity and projected mortality. Mortality after conventional surgical aortic valve replacement in cirrhotic patients depends upon the Child-Pugh class. In the past few years, transcatheter aortic valve replacement has progressively become the treatment of choice for high-risk patients with severe aortic stenosis. Here, we report the cases of 3 cirrhotic patients who became eligible for liver transplantation after successful transcatheter aortic valve replacement as bridge therapy.

Keywords: cardiovascular disease; cirrhosis; clinical research / practice; comorbidities; heart disease; liver disease; liver transplantation/hepatology.

MeSH terms

  • Aortic Valve / surgery
  • Aortic Valve Stenosis* / surgery
  • Humans
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / surgery
  • Liver Transplantation*
  • Risk Factors
  • Severity of Illness Index
  • Transcatheter Aortic Valve Replacement*
  • Treatment Outcome