Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge: A promising option for severe COVID-19

Farzaneh Dastan; Ali Saffaei; Seyed Mehdi Mortazavi; Hamidreza Jamaati; Nadia Adnani; Sasan Samiee Roudi; Arda Kiani; Atefeh Abedini; Seyed MohammadReza Hashemian

doi:10.1016/j.jgar.2020.04.024

Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge: A promising option for severe COVID-19

J Glob Antimicrob Resist. 2020 Jun:21:340-341. doi: 10.1016/j.jgar.2020.04.024. Epub 2020 Apr 27.

Authors

Farzaneh Dastan¹, Ali Saffaei², Seyed Mehdi Mortazavi³, Hamidreza Jamaati³, Nadia Adnani⁴, Sasan Samiee Roudi⁵, Arda Kiani⁶, Atefeh Abedini³, Seyed MohammadReza Hashemian⁷

Affiliations

¹ Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
² Student Research Committee, Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
³ Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁴ Nephrology Research Center, Department of Nephrology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
⁵ Infectious Research Center, Department of Infectious Disease, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
⁶ Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁷ Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: [email protected].

Abstract

Cytokine release syndrome is prevalent in severe cases of COVID-19. In this syndrome, an uncontrolled response of immune system occurs. Extracorporeal blood purification has been proven to effectively remove the released inflammatory cytokines. Here, we reported a successful case to represent our experience of extracorporeal blood purification in a patient with severe COVID-19.

Keywords: Acute respiratory distress syndrome; COVID-19; Continues renal replacement therapy; Hemoperfusion.

Publication types

Case Reports

MeSH terms

Betacoronavirus / isolation & purification
COVID-19
Coronavirus Infections / blood
Coronavirus Infections / diagnostic imaging
Coronavirus Infections / therapy*
Coronavirus Infections / virology
Cytokines / blood
Hemoperfusion / methods*
Humans
Interleukin-6 / blood
Iran
Lung / diagnostic imaging
Male
Middle Aged
Pandemics
Pneumonia, Viral / blood
Pneumonia, Viral / diagnostic imaging
Pneumonia, Viral / therapy*
Pneumonia, Viral / virology
Renal Replacement Therapy / methods*
SARS-CoV-2

Substances

Cytokines
Interleukin-6