The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development

Circ Res. 2020 Jul 31;127(4):550-552. doi: 10.1161/CIRCRESAHA.120.316932. Epub 2020 May 4.
No abstract available

Keywords: RNA editing; cell death; high-throughput nucleotide sequencing; myocardium; myocytes, cardiac.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine / metabolism*
  • Adenosine Deaminase / genetics
  • Adenosine Deaminase / physiology*
  • Animals
  • Apoptosis
  • Cell Proliferation
  • Cell Survival
  • Crosses, Genetic
  • Deamination
  • Gene Deletion
  • Heart / embryology*
  • Heart / growth & development
  • Inosine / metabolism*
  • Mice
  • Myocytes, Cardiac / physiology
  • RNA Editing / physiology*

Substances

  • Inosine
  • ADAR1 protein, mouse
  • Adenosine Deaminase
  • Adenosine