Medical versus surgical treatment in native hip and knee septic arthritis

Infect Dis Now. 2021 Mar;51(2):164-169. doi: 10.1016/j.medmal.2020.04.019. Epub 2020 May 5.

Abstract

Objective: Antibiotic treatment and arthroscopic or open drainage is the gold standard for septic arthritis. Full recovery takes time after surgery and hospital stay is longer than for arthrocentesis at the bedside. We aimed to evaluate the effectiveness of arthrocentesis (medical approach) versus a surgical approach.

Method: We retrospectively included 97 cases of native joint arthritis (hip and knee) between 2010 and 2017. The primary outcome was treatment failure of medical and surgical approaches (defined as surgical intervention within 7 days following diagnosis). Risk factors of failure were identified by univariable and multivariable logistic regression.

Results: We included 72 cases of knee arthritis, of which 43 and 29 were treated medically and surgically, respectively; 25 cases of hip arthritis, of which 8 and 17 were treated medically and surgically, respectively. Failure was observed in 39.2% of cases in the medical group and in 30.4% in the surgical group (P=0.2) (37.5% vs. 52.9% and 39.5% vs. 17.2% for hip and knee, respectively). The univariate analysis identified age and male sex as risk factors for failure (P=0.048 and P=0.02, respectively), but only age was independently associated with failure (P=0.04). Hospital length of stay was 12 days shorter in the medical group (21 vs. 33 days, P=0.02), sequelae were less frequent and less important in the medical group (31.7% vs. 60%).

Conclusion: The medical treatment seems to be as effective as the surgical treatment for native joint septic arthritis with a shorter hospital stay and better functional outcome. Further prospective studies are warranted.

Keywords: Arthritis; Arthrocentesis.

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious / drug therapy*
  • Arthritis, Infectious / microbiology
  • Arthritis, Infectious / surgery*
  • Arthrocentesis / methods
  • Arthroscopy / methods
  • Drainage / methods
  • Female
  • Hip Joint / surgery*
  • Humans
  • Knee Joint / surgery*
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / surgery
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents