Objective: To study the compliance of endoscopic screening for high-risk population of upper gastrointestinal cancer and relevant factors in urban areas of Henan Province, 2013-2017. Methods: The study participants were from the Cancer Screening Program in Urban Henan Province, China. From October 2013 to October 2017, 43 423 residents, who were evaluated as high-risk population for upper gastrointestinal cancer, were recruited from Zhengzhou, Zhumadian and Anyang. The cancer risk assessment questionnaire was used to collect basic demographic characteristics, dietary habits, living environment and habits, psychology and emotions, disease history and family history of cancer, and women's physiological and reproductive history. The data of endoscopic screening was obtained from hospitals participating in the Cancer Screening Program. Multivariate logistic regression model was applied to explore potential factors related to the compliance of endoscopic screening. Results: The age of study participants was(55.49±8.15) years old, and 44.00% (19 105) were male. About 18.41% of study subjects (7 996) took the endoscopic screening. The multivariate logistic regression analysis showed that females, individuals aged 45-64 years old, with junior high school education or above, unmarried/divorced/widowed, previous smoking, alcohol drinking, infrequent physical exercise, history of reflux esophagitis, history of superficial gastritis, history of gastric ulcer, history of duodenal ulcer, history of gastric polyps and family history of upper gastrointestinal cancer were more likely to accept endoscopic screening. Conclusion: The overall participation rate of endoscopic screening among high-risk population of upper gastrointestinal cancer was still low in urban areas of Henan Province. Gender, age, education, marital status, smoking, alcohol consumption, physical activity, history of upper gastrointestinal disease and family history of upper gastroin testinal cancer were associated with the compliance of endoscopic screening.
目的： 研究2013—2017年河南省城市地区上消化道癌高危人群的内镜筛查依从性及相关因素。 方法： 研究对象来源于河南省"城市癌症早诊早治项目"，于2013年10月至2017年10月，以郑州市、驻马店市和安阳市为研究地区，招募到43 423名当地40~74岁上消化道癌高危人群。采用患癌风险评估问卷收集基本人口学特征、饮食习惯、生活环境和习惯、心理和情绪、疾病既往史和癌症家族史以及女性的生理和生育史等信息；从项目参与医院获取参与消化道内镜检查的研究对象资料。采用多因素logistic回归模型分析内镜筛查参与的相关因素。 结果： 研究对象年龄为（55.49±8.15）岁，男性占44.00%（19 105名）；共有7 996名接受了内镜检查，总体参与率为18.41%。多因素logistic回归分析显示，女性、45~64岁、具有初中及以上学历、未婚/离异/丧偶、既往吸烟、正在饮酒、不经常体育锻炼、有反流性食管炎史、有浅表性胃炎史、有胃溃疡史、有十二指肠溃疡史、有胃息肉史和有上消化道癌家族史的人群接受内镜检查依从性较好（P<0.05）。 结论： 河南省城市上消化道癌高危人群的内镜筛查参与率较低。性别、年龄、学历、婚姻状态、吸烟、饮酒、体育锻炼、具有上消化道病史和癌症家族史与内镜筛查依从性相关。.
Keywords: Carcinoma; Compliance of screening; Cross-sectionalstudies.