Structure-Guided Design of a Group B Streptococcus Type III Synthetic Glycan-Conjugate Vaccine

Davide Oldrini; Linda Del Bino; Ana Arda; Filippo Carboni; Pedro Henriques; Francesca Angiolini; Jon I Quintana; Ilaria Calloni; Maria R Romano; Francesco Berti; Jesus Jimenez-Barbero; Immaculada Margarit; Roberto Adamo

doi:10.1002/chem.202002016

Structure-Guided Design of a Group B Streptococcus Type III Synthetic Glycan-Conjugate Vaccine

Chemistry. 2020 Jun 2;26(31):6944. doi: 10.1002/chem.202002016. Epub 2020 May 11.

Affiliations

¹ Research Center, GlaxoSmithKline Plc, Via Fiorentina 1, 53100, Siena, Italy.
² Chemical Glycobiology Lab, CIC bioGUNE, Basque Research Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Spain.
³ Ikerbasque, Basque Foundation for Science, 48013, Bilbao, Bizkaia, Spain.
⁴ Department Organic Chemistry II, University of the Basque Country UPV/EHU, 48940, Leioa, Bizkaia, Spain.

PMID: 32390224
DOI: 10.1002/chem.202002016

Abstract

Invited for the cover of this issue is the group of Roberto Adamo at GlaxoSmithKline Research Center, Siena, and colleagues at The University of the Basque Country and Basque Research Technology Alliance. The image depicts a tactical plan with the different elements of the research as part of the team. Read the full text of the article at 10.1002/chem.202000284.

MeSH terms

Humans
Polysaccharides / chemical synthesis*
Polysaccharides / chemistry
Streptococcus / chemistry*
Vaccines, Synthetic

Substances

Polysaccharides
Vaccines, Synthetic