Pleural Sarcoidosis and Occult Lymphatic Anthracosis: An Unusual Symptomatic Association

Eur J Case Rep Intern Med. 2020 Mar 17;7(5):001479. doi: 10.12890/2020_001479. eCollection 2020.

Abstract

Sarcoidosis is a chronic multisystemic inflammatory disease of unknown aetiology. Virtually any organ or system can be involved, resulting in a wide range of clinical presentation. Pleural sarcoidosis is rare. Pleural effusion can only be attributed to pleural sarcoidosis in the presence of pleural non-caseating epithelioid granulomas and after excluding other granulomatous diseases. Anthracosis is a pneumoconiosis associated with thoracic adenopathies and bronchial disease, and it is usually asymptomatic. The authors present a case of a middle-aged man hospitalized due to cough, right-sided pleuritic chest pain and trepopnoea.

Learning points: To pursue a systematic and exhaustive investigation of pleuraleffusion until a definitive diagnosis is established.To recognize atypical presentations of sarcoidosis with a high degree of suspicion whenever the initial investigation is inconclusive.

Keywords: Pleural effusion; anthracosis; exhaustive investigation; pleural sarcoidosis.